Description

Potassium [3-(Trifluoromethyl)Benzyl]Trifluoroborate is an organotrifluoroborate salt, a highly valuable class of reagents prized for their stability and utility in modern synthetic chemistry. This compound serves as a versatile and robust coupling partner in cross-coupling reactions, enabling the efficient construction of complex molecules. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries seeking reliable, high-purity building blocks for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl groups, crucial for synthesizing complex organic frameworks.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethylated aromatic motifs.
• Agrochemical Compound Development: Employed in creating novel herbicides, fungicides, and insecticides where the benzyltrifluoroborate moiety imparts desirable biological activity and stability.
• Material Science Research: Acts as a precursor for organic electronic materials, liquid crystals, and polymers requiring specific fluorinated aromatic structures.
• Medicinal Chemistry & Drug Discovery: Provides a stable handle for introducing the 3-(trifluoromethyl)benzyl group into candidate molecules during structure-activity relationship (SAR) studies.
• Fine Chemical and Specialty Chemical Production: Utilized in custom synthesis and contract manufacturing for high-value, low-volume chemical products.

Basic Information

Product Name	Potassium [3-(Trifluoromethyl)Benzyl]Trifluoroborate
CAS No.	1494466-25-9
Molecular Formula	C8H6BF6K
Molecular Weight	266.04 g/mol
Synonyms	Potassium (3-(Trifluoromethyl)benzyl)trifluoroborate; Potassium [(3-Trifluoromethyl)phenyl]methyltrifluoroborate; 3-(Trifluoromethyl)benzyltrifluoroborate Potassium Salt; [3-(Trifluoromethyl)benzyl]trifluoroboronic Acid Potassium Salt; Potassium (3-Trifluoromethylbenzyl)trifluoroboronate; (3-(Trifluoromethyl)phenyl)methanetrifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium [3-(Trifluoromethyl)Benzyl]Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon or nitrogen) when opening to prevent decomposition. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.