Description

n-(2,3-Dihydroxypropyl)-4-Hydroxybenzamide is a multifunctional chemical intermediate featuring both phenolic and amide groups with a hydrophilic dihydroxypropyl side chain. This unique structure makes it a valuable building block for synthesizing more complex molecules, particularly in the pharmaceutical and specialty chemical sectors. It is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), cosmetic actives, and advanced polymer additives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting neurological or metabolic pathways.
• Cosmetic & Personal Care Ingredients: Serves as a starting material for UV absorbers, antioxidants, and skin-conditioning agents.
• Polymer Modification: Used to introduce hydrophilic and cross-linking functionalities into resins and coatings.
• Bioconjugation & Linker Chemistry: The diol and phenolic groups are useful for creating cleavable linkers in bioconjugation and prodrug development.
• Research & Development: A versatile scaffold for medicinal chemistry and chemical biology research in academic and industrial settings.
• Specialty Surfactants: Potential use in synthesizing non-ionic surfactants with specific solubility profiles.

Basic Information

Product Name	n-(2,3-Dihydroxypropyl)-4-Hydroxybenzamide
CAS No.	1485506-79-3
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	4-Hydroxy-N-(2,3-dihydroxypropyl)benzamide; 1-(2,3-Dihydroxypropylamino)-4-hydroxy-1-oxobutane (incorrect but common misnomer); N-(2,3-Dihydroxypropyl)-4-hydroxybenzamide; 4-Hydroxybenzoic acid (2,3-dihydroxypropyl)amide; Glyceryl 4-hydroxybenzamide; DHB-Glyceryl Amide; Benzamide, N-(2,3-dihydroxypropyl)-4-hydroxy-
EINECS	Contact for details

Quality Control

Our n-(2,3-Dihydroxypropyl)-4-Hydroxybenzamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.