Description

4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid Hydrochloride is a high-purity, protected amino acid derivative of significant value in advanced organic synthesis. This compound matters as a critical chiral building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, particularly in central nervous system (CNS) and antiviral drug candidates.
• Peptidomimetic Chemistry: Serves as a constrained, rigid amino acid analog for designing and synthesizing peptide mimics with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands for asymmetric catalysis and metal complexes.
• Agrochemical Research: Employed as a building block for novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Facilitates the creation of molecular probes and tools for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high-purity, complex heterocyclic compounds.

Basic Information

Item	Details
Product Name	4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid Hydrochloride
CAS No.	1485427-12-0
Molecular Formula	C8H16ClNO3
Molecular Weight	209.67 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-pyran-4-carboxylic acid hydrochloride; 4-(Aminomethyl)tetrahydropyran-4-carboxylic acid HCl; 4-Carboxy-4-(aminomethyl)tetrahydropyran hydrochloride; 4-(Aminomethyl)-4-carboxytetrahydropyran hydrochloride; THP-Protected Aminomethyl Glycine Hydrochloride; (4-Carboxy-4-(aminomethyl)tetrahydro-2H-pyran) hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.