Description

4,5,6,7-Tetrahydrobenzofuran-6-Carboxylic Acid is a versatile bicyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused ring structure makes it a valuable intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials who require high-purity, reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced pesticides, herbicides, and plant growth regulators with specific activity profiles.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid bicyclic core.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tools to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and process development.
• Academic & Industrial R&D: Fundamental research reagent for methodology development in organic chemistry and catalysis studies.

Basic Information

Item	Details
Product Name	4,5,6,7-Tetrahydrobenzofuran-6-Carboxylic Acid
CAS No.	1481114-96-8
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	6-Carboxy-4,5,6,7-tetrahydrobenzofuran; 4,5,6,7-Tetrahydro-1-benzofuran-6-carboxylic acid; Tetrahydrobenzofuran-6-carboxylic acid; 6-Tetrahydrobenzofurancarboxylic acid; 1-Oxaspiro[2.5]octane-6-carboxylic acid (tautomeric form); 4,7-Dihydro-5H-benzofuran-6-carboxylic acid; 6-Carboxy-4,5,6,7-tetrahydro-1-benzofuran
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydrobenzofuran-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, providing full traceability and compliance data for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.