Description

8-((tert-Butoxycarbonyl)Amino)Octyl 4-Methylbenzenesulfonate is a high-purity, protected amine derivative designed for advanced organic synthesis and bioconjugation. This compound is a critical building block for researchers and manufacturers developing pharmaceuticals, diagnostic agents, and novel materials, offering a reactive tosylate leaving group and a Boc-protected amine for selective deprotection. It is essential for professionals in medicinal chemistry, peptide synthesis, and linker technology who require reliable, high-quality intermediates to ensure successful downstream reactions and product integrity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing long-chain amine functionalities.
• Bioconjugation & Linker Chemistry: Used to create cleavable or stable linkers for antibody-drug conjugates (ADCs), peptide-drug conjugates, and other targeted therapeutics.
• Peptide Modification: Enables the site-specific incorporation of functionalized alkyl chains into peptides and proteins for labeling or enhancing pharmacokinetic properties.
• Material Science: Acts as a monomer or surface-modifying agent in the development of functional polymers, hydrogels, and smart materials.
• Chemical Probe Development: Utilized in creating molecular probes and diagnostic reagents for biochemical and cellular research applications.
• Cross-linking Agent: Functions as a heterobifunctional cross-linker for coupling different biomolecules or materials under controlled conditions.

Basic Information

Product Name	8-((tert-Butoxycarbonyl)Amino)Octyl 4-Methylbenzenesulfonate
CAS No.	1472656-81-7
Molecular Formula	C20H33NO5S
Molecular Weight	399.55 g/mol
Synonyms	8-((Boc)Amino)Octyl Tosylate; 8-((tert-Butoxycarbonyl)Amino)Octyl Tosylate; 1-Octanol, 8-[[(1,1-dimethylethoxy)carbonyl]amino]-, 4-methylbenzenesulfonate; N-Boc-1,8-diaminooctane tosylate derivative; Boc-NH-(CH2)8-OTs; 8-(Boc-amino)octyl p-toluenesulfonate; tert-Butyl (8-(tosyloxy)octyl)carbamate
EINECS	Contact for details

Quality Control

Every batch of 8-((tert-Butoxycarbonyl)Amino)Octyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and GMP-grade applications, with comprehensive Certificates of Analysis (COA) provided for each lot, detailing results from HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.