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n-[(1S,2S)-2-(1-Pyrrolidinyl)Cyclohexyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea CAS NO 1471290-67-1
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CAS No.:1471290-67-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-[(1S,2S)-2-(1-Pyrrolidinyl)Cyclohexyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is a sophisticated chiral thiourea derivative designed for high-value applications in chemical synthesis and research. This compound is significant for its role as a potential intermediate or ligand in the development of pharmaceuticals and agrochemicals, where its stereochemistry and functional groups are critical for activity. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel therapeutics, catalysts, or diagnostic agents.
Application
- Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting metabolic or neurological disorders.
- Catalyst Ligand: Acts as a potential ligand for asymmetric catalysis, enabling the stereoselective synthesis of complex organic molecules.
- Glycobiology Research: Used as a tool compound in studying carbohydrate-protein interactions due to its acetylated glucopyranosyl moiety.
- Chemical Biology Probe: Employed in the development of probes for enzyme inhibition studies or cellular imaging.
- Agrochemical Development: Investigated as an intermediate for creating new, targeted crop protection agents with specific modes of action.
- Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and stereochemistry studies.
Basic Information
| Item | Details |
|---|---|
| Product Name | n-[(1S,2S)-2-(1-Pyrrolidinyl)Cyclohexyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea |
| CAS No. | 1471290-67-1 |
| Molecular Formula | C25H39N3O9S |
| Molecular Weight | 557.66 g/mol |
| Synonyms | (1S,2S)-2-(Pyrrolidin-1-yl)cyclohexyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosylcarbamimidothioate; 1-[(1S,2S)-2-(Pyrrolidin-1-yl)cyclohexyl]-3-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; Acetylated Glucosyl Thiourea Derivative; Chiral Cyclohexylpyrrolidine Thiourea; Peracetylated Glucopyranosyl Thiourea Ligand |
| EINECS | Contact for details |
Quality Control
Our n-[(1S,2S)-2-(1-Pyrrolidinyl)Cyclohexyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, and impurity profiles. We support compliance with cGMP standards for advanced intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






