Description

(5R)-6,7-Dihydro-5-(Phenylmethyl)-2-(2,4,6-Trimethylphenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate CAS NO 1469801-67-9 is a high-purity, advanced pharmaceutical intermediate and chiral ionic liquid salt. This compound matters for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and as a specialized reagent in asymmetric catalysis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Asymmetric Catalysis: Serves as a chiral catalyst or co-catalyst component in stereoselective organic transformations, such as alkylations and cycloadditions.
• Agrochemical Synthesis: Used in the research and development of advanced, enantiomerically pure pesticides and herbicides.
• Material Science Research: Investigated as a component in the development of specialized ionic liquids for electrochemical applications.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of optically active compounds.
• Academic & R&D: A valuable reagent for methodological studies in organic and medicinal chemistry within university and corporate laboratories.

Basic Information

Product Name	(5R)-6,7-Dihydro-5-(Phenylmethyl)-2-(2,4,6-Trimethylphenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate
CAS No.	1469801-67-9
Molecular Formula	C22H24N3·BF4
Molecular Weight	401.26 g/mol
Synonyms	(5R)-5-Benzyl-2-mesityl-5,6-dihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; (5R)-5-Benzyl-2-(2,4,6-trimethylphenyl)-5,6-dihydro-4H-pyrrolo[2,1-c][1,2,4]triazol-4-ium tetrafluoroborate; Chiral Pyrrolotriazolium Salt; (5R)-5-Benzyl-2-mesityl-4,5,6,7-tetrahydro-2H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate
EINECS	Contact for details

Quality Control

Our (5R)-6,7-Dihydro-5-(Phenylmethyl)-2-(2,4,6-Trimethylphenyl)-5H-Pyrrolo[2,1-C]-1,2,4-Triazolium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent decomposition. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.