Description

5-Oxaspiro[3.5]Nonane-8-Carboxylic Acid is a high-value spirocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the synthesis of complex, three-dimensional molecular architectures. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry: Used to introduce spirocyclic motifs that can improve metabolic stability, solubility, and binding affinity in lead optimization.
• Agrochemical Synthesis: Intermediate for developing new generation herbicides and fungicides with unique modes of action.
• Material Science Research: Serves as a precursor for specialty polymers and ligands with specific conformational properties.
• Chemical Biology: Useful as a probe or scaffold in the development of enzyme inhibitors and molecular tools.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	5-Oxaspiro[3.5]Nonane-8-Carboxylic Acid
CAS No.	1468691-26-0
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	8-Carboxy-5-oxaspiro[3.5]nonane; 5-Oxaspiro[3.5]nonane-8-carboxylic acid; 5-Oxaspiro[3.5]nonane-8-carboxylate; Spiro[3.5]nonane-8-carboxylic acid, 5-oxa-; 8-Carboxy-5-oxaspiro[3.5]nonane; Oxaspiro[3.5]nonane-8-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 5-Oxaspiro[3.5]Nonane-8-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) including HPLC purity, NMR confirmation, and residual solvent analysis is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.