Description

2H-Pyran-4-Carbonitrile, 4-(4-Aminophenyl)Tetrahydro- is a high-purity, functionalized heterocyclic compound featuring both a nitrile and a primary aromatic amine group. This unique bifunctional structure makes it a versatile and valuable building block for advanced organic synthesis, particularly in the development of complex molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates. The compound's reactivity allows for targeted modifications, enabling the exploration of new chemical spaces and the optimization of material properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing new herbicides, fungicides, or insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the development of advanced polymers, liquid crystals, or organic electronic materials due to its rigid aromatic-pyran structure and functional handles.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex heterocyclic architectures.

Basic Information

Product Name	2H-Pyran-4-Carbonitrile, 4-(4-Aminophenyl)Tetrahydro-
CAS No.	1462288-68-1
Molecular Formula	C12H12N2O
Molecular Weight	200.24 g/mol
Synonyms	4-(4-Aminophenyl)tetrahydro-2H-pyran-4-carbonitrile; Tetrahydro-4-(4-aminophenyl)-2H-pyran-4-carbonitrile; 4-(4-Aminophenyl)tetrahydropyran-4-carbonitrile; 4-Cyano-4-(4-aminophenyl)tetrahydropyran; 4-Aminophenyl-tetrahydropyran-4-carbonitrile; Building Block 1462288-68-1; CAS 1462288-68-1
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-4-Carbonitrile, 4-(4-Aminophenyl)Tetrahydro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications. Our commitment to consistent high purity and reliable supply supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its light-sensitive and easily oxidized nature, prolonged exposure to air, light, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.