Description

2,3-o-(1-Methylethylidene)-1-o-(Phenylmethyl)-α-L-Sorbofuranose 6-(4-Methylbenzenesulfonate) is a high-purity, protected sugar derivative and a critical chiral intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with precise stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and biotechnology industries for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of nucleoside-based antiviral and anticancer drugs.
• Process Chemistry: Used in route development and scale-up for the production of complex, stereochemically-defined active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Serves as a precursor for developing novel, chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Bioconjugation & Probe Development: Utilized in medicinal chemistry for the preparation of labeled compounds, molecular probes, and targeted drug delivery systems.
• Academic & Industrial R&D: Employed in research laboratories for exploring new synthetic methodologies and developing novel chemical entities.
• Carbohydrate Chemistry: A valuable substrate for studying glycosylation reactions and synthesizing complex oligosaccharides or glycomimetics.

Basic Information

Product Name	2,3-o-(1-Methylethylidene)-1-o-(Phenylmethyl)-α-L-Sorbofuranose 6-(4-Methylbenzenesulfonate)
CAS No.	1459288-93-7
Molecular Formula	C23H28O8S
Molecular Weight	464.53 g/mol
Synonyms	1-O-Benzyl-2,3-O-isopropylidene-α-L-sorbofuranose 6-tosylate; 1-O-Benzyl-2,3-O-isopropylidene-α-L-sorbofuranose 6-(p-toluenesulfonate); 6-O-Tosyl-1-O-benzyl-2,3-O-isopropylidene-α-L-sorbofuranose; Benzyl 2,3-O-isopropylidene-α-L-sorbofuranoside 6-tosylate; L-Sorbose derivative, 1-O-benzyl-2,3-O-isopropylidene-6-O-tosyl-; Protected L-sorbofuranose tosylate; (3aR,5R,6S,6aR)-5-(Benzyloxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-yl 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our 2,3-o-(1-Methylethylidene)-1-o-(Phenylmethyl)-α-L-Sorbofuranose 6-(4-Methylbenzenesulfonate) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and reactivity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.