Description

3-Bromo-6-Fluoroimidazo[1,2-B]Pyridazine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique fused ring structure, which incorporates both bromine and fluorine atoms, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Potential building block for creating specialty polymers, liquid crystals, or organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Cross-Coupling Reactions: The bromine atom serves as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to introduce diverse substituents.
• Nucleophilic Aromatic Substitution: The fluorine atom can be selectively displaced by various nucleophiles, allowing for further functionalization of the heterocyclic core.

Basic Information

Product Name	3-Bromo-6-Fluoroimidazo[1,2-B]Pyridazine
CAS No.	1454814-05-1
Molecular Formula	C6H3BrFN3
Molecular Weight	216.01 g/mol
Synonyms	3-Bromo-6-fluoroimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 3-bromo-6-fluoro-; 6-Fluoro-3-bromoimidazo[1,2-b]pyridazine; 1454814-05-1; 3-Bromo-6-fluoro-[1,2,4]triazolo[4,3-b]pyridazine (common misnomer); 3-Br-6-F-imidazo[1,2-b]pyridazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoroimidazo[1,2-B]Pyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.