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tert-Butyl (2-((3-(4-Carbamoylphenyl)Imidazo[1,2-B]Pyridazin-6-Yl)Amino)Ethyl)(Methyl)Carbamate CAS NO 1454808-95-7
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CAS No.:1454808-95-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
tert-Butyl (2-((3-(4-Carbamoylphenyl)Imidazo[1,2-B]Pyridazin-6-Yl)Amino)Ethyl)(Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and other therapeutic areas requiring sophisticated molecular scaffolds.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
- Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of potent and selective kinase inhibitors.
- Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and cellular signaling mechanisms.
- Preclinical Candidate Synthesis: Integral to the multi-step synthesis of compounds selected for advanced preclinical evaluation.
- Custom Synthesis Projects: Supplied to contract research organizations (CROs) and CDMOs for bespoke chemical synthesis.
Basic Information
| Product Name | tert-Butyl (2-((3-(4-Carbamoylphenyl)Imidazo[1,2-B]Pyridazin-6-Yl)Amino)Ethyl)(Methyl)Carbamate |
| CAS No. | 1454808-95-7 |
| Molecular Formula | C21H27N7O3 |
| Molecular Weight | 425.49 g/mol |
| Synonyms | tert-Butyl N-[2-[[3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl]amino]ethyl]-N-methylcarbamate; BOC-Protected Imidazopyridazine Amine Derivative; 1454808-95-7; (2-((3-(4-Carbamoylphenyl)Imidazo[1,2-B]Pyridazin-6-Yl)Amino)Ethyl)(Methyl)Carbamic Acid tert-Butyl Ester; tert-Butyl Methyl(2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)carbamate |
| EINECS | Contact for details |
Quality Control
Our tert-Butyl (2-((3-(4-Carbamoylphenyl)Imidazo[1,2-B]Pyridazin-6-Yl)Amino)Ethyl)(Methyl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under inert atmosphere or dry conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC/MS) | Conforms |
| Purity (HPLC) | ≥ 97.0% |
| Related Substances (HPLC) | Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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