Description

(3-Chloro-5-(Trifluoromethoxy)Phenyl)Boronic Acid is a high-purity, synthetically valuable organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and advanced materials.

Application

This versatile boronic acid derivative serves as a key reagent in numerous synthetic pathways:

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for creating biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Construction of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Preparation: Used to create sophisticated ligands for catalysis and molecular recognition.
• Chemical Biology Probes: Synthesis of tool compounds for studying biological pathways and protein function.

Basic Information

Product Name	(3-Chloro-5-(Trifluoromethoxy)Phenyl)Boronic Acid
CAS No.	1451393-40-0
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.38 g/mol
Synonyms	[3-Chloro-5-(trifluoromethoxy)phenyl]boronic acid; (3-Chloro-5-(trifluoromethoxyl)phenyl)boronic acid; Boronic acid, B-[3-chloro-5-(trifluoromethoxy)phenyl]-; 3-Chloro-5-trifluoromethoxyphenylboronic acid; 3-Chloro-5-(trifluoromethoxy)benzeneboronic acid; CAS 1451393-40-0
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-(Trifluoromethoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.