Description

1-Hydroxyhept-6-Yn-3-One is a specialized alkyne-containing hydroxy ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique bifunctional molecular architecture, which provides two distinct reactive handles—a terminal alkyne and a ketone group—for constructing complex molecular frameworks. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as click chemistry, cross-coupling reactions, and the synthesis of novel bioactive molecules or polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing alkyne functionalities for subsequent bioconjugation or labeling.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or plant growth regulators that require specific alkyne motifs for activity or further derivatization.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, or advanced materials with tailored properties.
• Click Chemistry Reagent: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and material surface functionalization.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex natural product analogs, fragrances, or fine chemicals.
• Bioconjugation & Probe Development: Enables the attachment of fluorescent tags, affinity labels, or other reporter molecules to biomolecules for diagnostic and research applications.

Basic Information

Product Name	1-Hydroxyhept-6-Yn-3-One
CAS No.	1450754-40-1
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	6-Heptyn-3-one, 1-hydroxy-; 1-Hydroxy-6-heptyn-3-one; 3-Heptyn-1-ol-5-one; Hept-6-yn-3-one, 1-hydroxy-; 1-Hydroxyhept-6-yn-3-one; 5-Hydroxy-1-heptyn-3-one; 3-Oxo-1-heptyn-5-ol
EINECS	Contact for details

Quality Control

Every batch of 1-Hydroxyhept-6-Yn-3-One is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards and customer-specific requirements. Comprehensive analytical techniques, including HPLC, GC, NMR, and IR spectroscopy, are employed to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.