Description

2-Propanesulfinamide, n-[(1R)-1-(2-Fluorophenyl)Propyl]-2-Methyl-, [S(S)] is a high-value, chiral sulfinamide building block of significant importance in modern asymmetric synthesis. Its primary value lies in its role as a versatile chiral auxiliary and ligand, enabling the stereoselective construction of complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemical control.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce stereoselectivity in key bond-forming reactions such as additions to carbonyl groups.
• Pharmaceutical Intermediate: A critical building block for the research and development of novel, stereochemically defined drug candidates.
• Ligand for Catalysis: Can be utilized in the preparation of chiral catalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed in the development of chiral active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	2-Propanesulfinamide, n-[(1R)-1-(2-Fluorophenyl)Propyl]-2-Methyl-, [S(S)]
CAS No.	1448902-46-2
Molecular Formula	C13H18FNOS
Molecular Weight	255.35 g/mol
Synonyms	(S)-N-[(1R)-1-(2-Fluorophenyl)propyl]-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide, N-[(1R)-1-(2-fluorophenyl)propyl]-; N-[(1R)-1-(2-Fluorophenyl)propyl]-2-methyl-2-propanesulfinamide, (S)-; (S)-N-[(1R)-1-(2-Fluorophenyl)propyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide Derivative; (S)-2-Methyl-N-[(1R)-1-(2-fluorophenyl)propyl]propane-2-sulfinamide
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral HPLC, and NMR to confirm identity, chemical purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.