Description

Aminotriclabendazole Hydrochloride CAS NO 1448346-37-9 is a high-purity pharmaceutical intermediate and research chemical, primarily utilized in the synthesis of advanced anthelmintic agents. Its significance lies in its role as a key building block for developing potent parasitic treatments, offering critical value for manufacturers requiring reliable and consistent raw material quality. This compound is essential for research institutions and pharmaceutical companies focused on veterinary medicine and parasitology, where precise chemical synthesis is paramount for product efficacy and safety.

Application

• Primary Intermediate for the synthesis of Triclabendazole and related benzimidazole anthelmintic drugs.
• Active Pharmaceutical Ingredient (API) development for veterinary formulations targeting liver fluke (Fasciola hepatica) infections.
• Research & Development of novel antiparasitic compounds in academic and industrial laboratories.
• Reference Standard for analytical method development and quality control in pharmaceutical manufacturing.
• Precursor in the production of more complex, targeted therapeutic agents.

Basic Information

Product Name	Aminotriclabendazole Hydrochloride
CAS No.	1448346-37-9
Molecular Formula	C14H10Cl3N3O2 • HCl
Molecular Weight	383.61 g/mol (Free base: 347.61)
Synonyms	5-Chloro-6-(2,3-dichlorophenoxy)-2-aminobenzimidazole Hydrochloride; 2-Amino-5-chloro-6-(2,3-dichlorophenoxy)benzimidazole Hydrochloride; Aminotriclabendazole HCl; 6-Amino-5-chloro-2-(2,3-dichlorophenoxy)benzimidazole Hydrochloride; Triclabendazole Aminated Derivative HCl; ATBZ HCl; CAS 1448346-37-9
EINECS	Contact for details

Quality Control

Our Aminotriclabendazole Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for pharmaceutical R&D and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, purity, and impurity profiles. Our quality commitment aligns with cGMP principles, ensuring the material meets the stringent requirements for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.