Description

4-(Trifluoromethyl)Pyridazine-3-Carboxylic Acid is a high-value fluorinated pyridazine derivative, serving as a critical building block in advanced organic synthesis. Its trifluoromethyl group and carboxylic acid functionality make it a versatile intermediate for creating compounds with enhanced metabolic stability, lipophilicity, and bioavailability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Precursor: Employed in the synthesis of advanced functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	4-(Trifluoromethyl)Pyridazine-3-Carboxylic Acid
CAS No.	1448156-15-7
Molecular Formula	C6H3F3N2O2
Molecular Weight	192.10 g/mol
Synonyms	3-Pyridazinecarboxylic acid, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-3-pyridazinecarboxylic acid; 4-Trifluoromethylpyridazine-3-carboxylic acid; 1448156-15-7; 4-(Trifluoromethyl)pyridazine-3-carboxylic acid; 4-(Trifluoromethyl)-1,2-diazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyridazine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.