Description

(R)-2-Methyltetrahydro-2H-Pyran-2-Carboxylic Acid CAS NO 1447943-69-2 is a chiral, non-natural carboxylic acid featuring a tetrahydropyran ring, serving as a valuable building block in asymmetric synthesis. This compound is critical for the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals where stereochemical purity is paramount. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with high enantiomeric excess.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis.
• Flavor and Fragrance Industry: Employed in the synthesis of complex, stereodefined aroma chemicals and flavoring agents.
• Academic and R&D: A versatile starting material for methodological development in organic chemistry and medicinal chemistry research.
• Specialty Polymers: Potential monomer for creating polymers with specific chiral architectures and properties.

Basic Information

Product Name	(R)-2-Methyltetrahydro-2H-Pyran-2-Carboxylic Acid
CAS No.	1447943-69-2
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(R)-2-Methyloxane-2-carboxylic acid; (R)-2-Methyltetrahydropyran-2-carboxylic acid; (2R)-2-Methyloxane-2-carboxylic acid; (R)-2-Methyl-2-tetrahydropyrancarboxylic acid; (R)-MTHP-2-COOH; (R)-2-Methyltetrahydro-2H-pyran-2-carboxylic acid; (2R)-2-Methyltetrahydro-2H-pyran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (R)-2-Methyltetrahydro-2H-Pyran-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure high enantiomeric purity and identity confirmation via spectroscopic methods. We provide Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and consistent material for critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.