Description

tert-Butyl ((2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazol-7-Yl)Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering a protected amine functionality essential for constructing active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a key starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.
• Peptidomimetic Synthesis: Employed in the construction of peptide-like molecules designed to mimic natural peptides for enhanced stability and bioavailability.
• Heterocyclic Compound Library Synthesis: A valuable scaffold for generating diverse chemical libraries for high-throughput screening in drug discovery.
• Custom Synthesis Projects: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule synthesis.

Basic Information

Product Name	tert-Butyl ((2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazol-7-Yl)Methyl)Carbamate
CAS No.	1445951-11-0
Molecular Formula	C13H21N3O3
Molecular Weight	267.33 g/mol
Synonyms	Boc-Protected Tetrahydropyranopyrazole Amine; tert-Butyl N-[(2,4,5,7-tetrahydropyrano[3,4-c]pyrazol-7-yl)methyl]carbamate; 7-[(tert-Butoxycarbonylamino)methyl]-2,4,5,7-tetrahydropyrano[3,4-c]pyrazole; (2,4,5,7-Tetrahydropyrano[3,4-c]pyrazol-7-yl)methyl-carbamic acid tert-butyl ester; tert-Butyl ((2,4,5,7-tetrahydropyrano[3,4-c]pyrazol-7-yl)methyl)carbamate; 1445951-11-0; Boc-THP-pyrazole-methylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl ((2,4,5,7-Tetrahydropyrano[3,4-C]Pyrazol-7-Yl)Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.