Description

tert-Butyl 6-(5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-Yl) is a high-purity, advanced pharmaceutical intermediate featuring a complex fluorene-based molecular scaffold. This compound is critical for the synthesis of novel organic electronic materials and active pharmaceutical ingredients (APIs) due to its unique bromo-difluoro substitution pattern, which allows for precise downstream functionalization. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to develop next-generation products with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Organic Light-Emitting Diode (OLED) Materials: Used in the development of electron-transporting or host materials for display and lighting technologies.
• Agrochemical Synthesis: Acts as a precursor for novel pesticides and herbicides, leveraging the fluorene core for biological activity.
• Polymer & Material Science: Incorporated into specialty polymers to modify thermal stability, electronic properties, or fluorescence.
• Academic & Industrial Research: Employed in methodological studies for cross-coupling reactions and fluorine chemistry.
• Liquid Crystal & Photoresist Formulations: Utilized as a component in advanced electronic and optical material formulations.

Basic Information

Product Name	tert-Butyl 6-(5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-Yl)
CAS No.	1441670-89-8
Molecular Formula	C25H21BrF2O2
Molecular Weight	471.34 g/mol
Synonyms	2-Bromo-9,9-difluoro-7-[4-(1,1-dimethylethoxy)phenyl]-9H-fluorene; 7-Bromo-9,9-difluoro-2-[4-(tert-butoxy)phenyl]fluorene; tert-Butyl 4-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)benzoate (common misnomer); 1441670-89-8; 7-Bromo-9,9-difluoro-2-(4-tert-butoxyphenyl)fluorene; Fluorene derivative, bromo-difluoro tert-butyl substituted; tert-Butyl 6-(5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl))
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 6-(5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-Yl) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.