Description

1-(4-Fluorophenoxy)-3-{[4-Methyl-5-(Trifluoromethyl)-4H-1,2,4-Triazol-3-Yl]Thio}Propan-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-triazole-thioether structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in oncology, antiviral, and anti-inflammatory research pipelines.
• Agrochemical Research: Serves as a key synthon for developing new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated triazole moiety.
• Chemical Biology Probes: Used in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold for probing enzyme interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis and process development.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique surface properties.

Basic Information

Product Name	1-(4-Fluorophenoxy)-3-{[4-Methyl-5-(Trifluoromethyl)-4H-1,2,4-Triazol-3-Yl]Thio}Propan-2-Ol
CAS No.	1440535-63-6
Molecular Formula	C13H13F4N3O2S
Molecular Weight	351.32 g/mol
Synonyms	1-(4-Fluorophenoxy)-3-[(4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio]propan-2-ol; 2-Propanol, 1-(4-fluorophenoxy)-3-[[4-methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]thio]-; CAS 1440535-63-6; 4-Methyl-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol derivative; Fluorophenoxy triazolyl thioether propanol; Advanced trifluoromethyl triazole intermediate.
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenoxy)-3-{[4-Methyl-5-(Trifluoromethyl)-4H-1,2,4-Triazol-3-Yl]Thio}Propan-2-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.