Description

n-[(1R,2R)-2-(Dimethylamino)-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)- Thiourea is a sophisticated chiral thiourea derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. Its complex structure, featuring both a glucopyranosyl moiety and a chiral diphenylethylamine backbone, makes it a valuable ligand and building block for asymmetric catalysis and drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors developing novel active ingredients and chiral catalysts.

Application

• Asymmetric Catalysis: Serves as a highly effective chiral organocatalyst or ligand for enantioselective synthesis reactions.
• Pharmaceutical Intermediate: A critical building block in the research and development of new therapeutic agents, particularly for glycosylated or chiral molecules.
• Glycochemistry Research: Used in the study and synthesis of complex carbohydrate derivatives and glycoconjugates.
• Agrochemical Development: Employed as a precursor in creating novel, targeted pesticides and herbicides with specific chiral activity.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme mechanisms and biological recognition events.
• Material Science: Potential use in developing chiral stationary phases for chromatographic separation of enantiomers.

Basic Information

Product Name	n-[(1R,2R)-2-(Dimethylamino)-1,2-Diphenylethyl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)- Thiourea
CAS No.	1440198-44-6
Molecular Formula	C33H41N3O9S
Molecular Weight	655.76 g/mol
Synonyms	N-[(1R,2R)-2-(Dimethylamino)-1,2-diphenylethyl]-N'-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thiourea; (1R,2R)-N-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-N'-[2-(dimethylamino)-1,2-diphenylethyl]thiourea; Chiral Glucosyl Thiourea Derivative; Acetylated Glucopyranosyl Thiourea Catalyst; DADP-GlcNAc Thiourea
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and Mass Spectrometry for characterization, ensuring the product meets the exacting standards required for pharmaceutical and catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.