Description

1-(4-Methoxybenzyl)Cyclobutanecarboxylicacid is a specialized organic building block featuring a cyclobutane core substituted with a carboxylic acid group and a 4-methoxybenzyl moiety. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active ingredients, where its rigid cyclobutane ring can impart desirable conformational and metabolic properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides, where the methoxybenzyl group can influence bioavailability and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Potential building block for advanced polymers or liquid crystals due to its rigid-rod-like structure.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function or cellular pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(4-Methoxybenzyl)Cyclobutanecarboxylicacid
CAS No.	1439903-09-9
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	1-[(4-Methoxyphenyl)methyl]cyclobutanecarboxylic acid; 4-Methoxybenzylcyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-[(4-methoxyphenyl)methyl]-; 1-(4-Methoxybenzyl)cyclobutane-1-carboxylic acid; p-Methoxybenzyl cyclobutanecarboxylate (precursor form); 1-(p-Methoxybenzyl)cyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Methoxybenzyl)Cyclobutanecarboxylicacid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports compliance in cGMP (current Good Manufacturing Practice) environments for non-clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.