Description

1-(4-Fluorobenzyl)Cyclobutanecarboxylicacid is a high-purity fluorinated cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a cyclobutane ring with a fluorinated benzyl group, makes it an invaluable intermediate for creating novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications requiring precise molecular architecture and the introduction of fluorine atoms to modulate bioactivity and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity, metabolic stability, and target binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where the cyclobutane and fluorinated aromatic components can influence material rigidity and optical properties.
• Chemical Biology Probe: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	1-(4-Fluorobenzyl)Cyclobutanecarboxylicacid
CAS No.	1439900-45-4
Molecular Formula	C12H13FO2
Molecular Weight	208.23 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]cyclobutanecarboxylic acid; 4-Fluorobenzylcyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)cyclobutanecarboxylic acid; 1-(4-Fluorobenzyl)-1-cyclobutanecarboxylic acid; 1-(4-Fluorobenzyl)cyclobutane-1-carboxylic acid; 1-(p-Fluorobenzyl)cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorobenzyl)Cyclobutanecarboxylicacid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or cGMP-grade requirements. Our quality system is designed to guarantee batch-to-batch consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.