Description

4-(Azetidin-3-Yl)Tetrahydro-2H-Pyran-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry, crucial for modern drug discovery. This compound serves as a key building block in the synthesis of complex molecules, offering researchers a reliable and consistent starting material. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing novel molecular scaffolds with potential biological activity.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes from laboratory to pilot plant scale.
• Protease Inhibitor Synthesis: Its structural features make it valuable for constructing inhibitors of serine and cysteine proteases.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying enzyme function and cellular signaling pathways.

Basic Information

Product Name	4-(Azetidin-3-Yl)Tetrahydro-2H-Pyran-2-One Hydrochloride
CAS No.	1439818-48-0
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	4-(Azetidin-3-yl)oxan-2-one hydrochloride; 2H-Pyran-2-one, tetrahydro-4-(3-azetidinyl)-, hydrochloride; 4-(Azetidin-3-yl)tetrahydro-2H-pyran-2-one HCl; 3-(5-Oxooxan-4-yl)azetidine hydrochloride; Azetidine, 3-(5-oxotetrahydro-2H-pyran-4-yl)-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-(Azetidin-3-Yl)Tetrahydro-2H-Pyran-2-One Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.