Description

3-Benzyloxy-5-Fluoro-Phenylamine is a high-purity aromatic amine derivative featuring both benzyloxy and fluoro substituents. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for advanced synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the fluorine moiety for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other advanced organic transformations.
• Material Science Research: Intermediate for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing complex chromophores and fluorophores used in imaging and display technologies.
• Academic and R&D Laboratories: Used in medicinal chemistry and process chemistry research for exploring new synthetic pathways and drug candidates.

Basic Information

Product Name	3-Benzyloxy-5-Fluoro-Phenylamine
CAS No.	1438272-88-8
Molecular Formula	C₁₃H₁₂FNO
Molecular Weight	217.24 g/mol
Synonyms	3-(Benzyloxy)-5-fluoroaniline; 5-Fluoro-3-(phenylmethoxy)aniline; 3-Benzyloxy-5-fluoroaniline; 1-Benzyloxy-3-amino-5-fluorobenzene; 5-Fluoro-3-benzyloxyaniline; 3-Amino-5-fluorophenyl benzyl ether; Benzenamine, 3-(benzyloxy)-5-fluoro-
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-5-Fluoro-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.