Description

Potassium 3,3,3-Trifluoropropane-1-Trifluoroborate is a versatile organoboron reagent featuring a trifluoromethyl group and a potassium trifluoroborate moiety. This compound is valued for its enhanced stability and utility in cross-coupling reactions compared to traditional boronic acids. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of complex fluorinated molecules. Its unique structure makes it a critical building block for introducing trifluoromethylated segments into target compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a stable organotrifluoroborate reagent for constructing C-C bonds in the synthesis of fluorinated pharmaceuticals and agrochemicals.
• Fluorine-Containing Building Block: For the introduction of the 3,3,3-trifluoropropyl group into complex organic molecules to modulate their lipophilicity, metabolic stability, and bioavailability.
• Advanced Material Synthesis: Used in the research and development of fluorinated polymers, liquid crystals, and organic electronic materials.
• Medicinal Chemistry & Drug Discovery: A key intermediate in the preparation of candidate drug molecules that incorporate fluorine for enhanced biological activity.
• Agrochemical Intermediate: Employed in the synthesis of novel herbicides, pesticides, and fungicides with improved efficacy and environmental profiles.
• Catalysis and Ligand Development: Serves as a precursor for ligands or catalysts used in asymmetric synthesis and other specialized catalytic processes.

Basic Information

Item	Detail
Product Name	Potassium 3,3,3-Trifluoropropane-1-Trifluoroborate
CAS No.	1430722-07-8
Molecular Formula	C3H4BF6K
Molecular Weight	207.97 g/mol
Synonyms	Potassium (3,3,3-Trifluoropropyl)trifluoroborate; 3,3,3-Trifluoropropyltrifluoroborate Potassium Salt; Potassium 3,3,3-Trifluoropropyltrifluoroborate; (3,3,3-Trifluoropropyl)potassium trifluoroborate; Potassium Trifluoro(3,3,3-trifluoropropyl)borate; K-3,3,3-Trifluoropropyl-BF3; 1-Trifluoroborato-3,3,3-trifluoropropane Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium 3,3,3-Trifluoropropane-1-Trifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR (1H, 11B, 19F) and HPLC to confirm identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.