Description

Potassium 1-Boc-Pyrrolidine-3-Trifluoroborate is a high-value organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its primary value lies in its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials. The product is supplied as a high-purity solid, with CAS number 1430219-72-9.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those containing substituted pyrrolidine scaffolds common in bioactive molecules.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Employed in the creation of organic electronic materials, ligands for catalysis, and other specialty polymers.
• Chemical Biology & Proteomics: Acts as a building block for synthesizing molecular probes and activity-based protein profiling reagents.
• Academic & Process R&D: A valuable reagent for methodology development and scaling up synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	Potassium 1-Boc-Pyrrolidine-3-Trifluoroborate
CAS No.	1430219-72-9
Molecular Formula	C9H15BF3KNO2
Molecular Weight	270.13 g/mol
Synonyms	Potassium (1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)trifluoroborate; 1-Boc-3-Trifluoroboratomethylpyrrolidine Potassium Salt; 1-(tert-Butoxycarbonyl)-3-(trifluoroborato)pyrrolidine Potassium Salt; 1-Boc-3-Pyrrolidine Trifluoroborate Potassium Salt; Potassium 1-(tert-Butoxycarbonyl)-3-trifluoroboratopyrrolidine; Potassium 1-N-Boc-pyrrolidine-3-trifluoroborate; Potassium 3-Trifluoroborato-1-Boc-pyrrolidine
EINECS	Contact for details

Quality Control

Our Potassium 1-Boc-Pyrrolidine-3-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain long-term stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (NMR)	≥ 97%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.