Description

Potassium n-Boc-Piperidinyl-4-Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, particularly Suzuki-Miyaura cross-couplings, under mild conditions. It is an essential intermediate for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing the piperidine scaffold common in CNS and oncology therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed coupling with aryl/heteroaryl halides.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring specific piperidine-based architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology & Probe Development: Utilized for the site-specific incorporation of trifluoroborate handles into biomolecules for imaging or interaction studies.
• Process Chemistry & Scale-Up: Provides a reliable and scalable intermediate for optimizing synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Potassium n-Boc-Piperidinyl-4-Trifluoroborate
CAS No.	1430219-71-8
Molecular Formula	C11H19BF3KNO2
Molecular Weight	304.09 g/mol
Synonyms	Potassium (tert-Butoxycarbonyl)piperidin-4-yltrifluoroborate; Potassium 4-(N-Boc-amino)piperidin-1-yltrifluoroborate; 1-Boc-4-(Trifluoroborato)piperidine Potassium Salt; 4-(Trifluoroborato)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester potassium salt; n-Boc-4-Piperidine Trifluoroborate Potassium Salt; Potassium 1-Boc-4-trifluoroboratopiperidine; Potassium 4-(N-Boc)piperidinyltrifluoroborate; Potassium 1-N-Boc-4-piperidinyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium n-Boc-Piperidinyl-4-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
19F NMR Purity	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.