Description

Potassium 2-(Pyrrolidin-1-Yl)Ethoxymethyltrifluoroborate is a specialized organotrifluoroborate salt, a valuable class of reagents in modern synthetic chemistry. This compound is prized for its enhanced stability and solubility compared to traditional boronic acids, enabling more robust and efficient cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and this stable organoboron species.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing complex heterocyclic systems.
• Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides requiring specific structural motifs.
• Ligand and Catalyst Preparation: Serves as a building block for creating sophisticated ligands and organometallic catalysts.
• Material Science Research: Used in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Peptide Modification and Bioconjugation: Facilitates the site-specific introduction of functional groups into biomolecules.
• Radiolabeling Precursor: Potential use as a precursor in the synthesis of compounds for positron emission tomography (PET) imaging.
• Scale-up Process Chemistry: Its stability makes it suitable for optimization and scale-up of coupling reactions in pilot plants and manufacturing.

Basic Information

Product Name	Potassium 2-(Pyrrolidin-1-Yl)Ethoxymethyltrifluoroborate
CAS No.	1430082-96-4
Molecular Formula	C7H14BF3KNO
Molecular Weight	247.10 g/mol
Synonyms	Potassium (2-(Pyrrolidin-1-yl)ethoxy)methyltrifluoroborate; Potassium Trifluoro((2-(pyrrolidin-1-yl)ethoxy)methyl)borate; 2-(1-Pyrrolidinyl)ethoxymethyltrifluoroborate Potassium Salt; (2-(Pyrrolidin-1-yl)ethoxy)methyltrifluoroborate Potassium; K-2-Pyrrolidin-1-yl-EOM-BF3; Potassium (2-(Pyrrolidino)ethoxy)methyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 2-(Pyrrolidin-1-Yl)Ethoxymethyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay/purity, identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers requiring material for advanced process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (NMR/HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Potassium Content	15.0 - 16.5%
Boron Content	4.0 - 4.5%
Fluorine Content	22.0 - 24.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.