Description

[1,1'-Biphenyl]-3-Carboxylic Acid, 3'-Amino-5'-Chloro-2'-Hydroxy- is a high-purity, multi-functional biphenyl derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring carboxylic acid, amino, chloro, and hydroxy substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targeted therapies and small molecule APIs.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Used to create chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Functional Material Research: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Serves as a core structure for synthesizing complex colorants and optical brighteners.
• Academic and R&D Laboratories: Valuable reagent for methodological studies in organic chemistry and material science.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Carboxylic Acid, 3'-Amino-5'-Chloro-2'-Hydroxy-
CAS No.	1428987-67-0
Molecular Formula	C₁₃H₁₀ClNO₃
Molecular Weight	263.67 g/mol
Synonyms	3'-Amino-5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; 5-Chloro-2'-hydroxy-3'-aminobiphenyl-3-carboxylic acid; 3-Amino-5-chloro-2-hydroxybiphenyl-3'-carboxylic acid; 3'-Amino-5'-chloro-2'-hydroxybiphenyl-3-carboxylic acid; Biphenyl-3-carboxylic acid, 3'-amino-5'-chloro-2'-hydroxy-; ACHB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Carboxylic Acid, 3'-Amino-5'-Chloro-2'-Hydroxy- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.