Description

Potassium (1-Boc-Indol-3-Yl)Trifluoroboranuide is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic organic chemistry. It serves as a stable, air- and moisture-tolerant precursor for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex indole-containing molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based active pharmaceutical ingredients (APIs) and drug candidates.
• Suzuki-Miyaura Cross-Coupling: A stable, bench-stable boronic acid surrogate for palladium-catalyzed C-C bond formation, offering superior handling compared to boronic acids.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides containing the indole scaffold.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and functional polymers.
• Chemical Biology & Probe Development: Facilitates the synthesis of labeled indole derivatives for biochemical assays and diagnostic tools.
• Academic & Process R&D: A valuable reagent for methodology development and scaling up synthetic routes in both academic and industrial laboratories.

Basic Information

Product Name	Potassium (1-Boc-Indol-3-Yl)Trifluoroboranuide
CAS No.	1428884-69-8
Molecular Formula	C13H14BF3KNO2
Molecular Weight	325.16 g/mol
Synonyms	Potassium (1-tert-Butoxycarbonyl-1H-indol-3-yl)trifluoroborate; Potassium (1-Boc-1H-indol-3-yl)trifluoroborate; 1-Boc-3-Indolyltrifluoroborate Potassium Salt; (1-Boc-indol-3-yl)trifluoroboronic acid potassium salt; 3-Trifluoroboratomethyl-1H-indole-1-carboxylic acid tert-butyl ester potassium salt; Potassium 1-(tert-Butoxycarbonyl)-1H-indol-3-yltrifluoroborate; 1-Boc-3-Trifluoroboratomethylindole Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium (1-Boc-Indol-3-Yl)Trifluoroboranuide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.