Description

4-Methyl-5-(Tributylstannyl)Thiazole is a high-purity organotin intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the preparation of complex molecules, particularly in pharmaceutical research and material science. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and electronics industries for applications requiring precise metal-mediated coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates containing thiazole heterocycles.
• Agrochemical Synthesis: Used in the development of new generation fungicides and pesticides where the tributylstannyl group facilitates efficient cross-coupling steps.
• Material Science Research: Employed in the creation of specialized polymers, ligands for catalysis, and organic electronic materials.
• Stille Cross-Coupling Reactions: Acts as a versatile organotin reagent for palladium-catalyzed carbon-carbon bond formation, a fundamental transformation in modern organic chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Academic & Industrial R&D: A valuable tool for method development and exploratory synthesis in both university and corporate research laboratories.

Basic Information

Product Name	4-Methyl-5-(Tributylstannyl)Thiazole
CAS No.	1428761-41-4
Molecular Formula	C16H31NSSn
Molecular Weight	388.20 g/mol
Synonyms	5-(Tributylstannyl)-4-methylthiazole; 4-Methyl-5-tributylstannylthiazole; Tributyl(4-methylthiazol-5-yl)stannane; 4-Methyl-5-(tributylstannyl)-1,3-thiazole; Thiazole, 4-methyl-5-(tributylstannyl)-; Stannane, tributyl(4-methyl-5-thiazolyl)-
EINECS	Contact for details

Quality Control

Our 4-Methyl-5-(Tributylstannyl)Thiazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive (hygroscopic) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	30.0 - 31.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.