Description

4-Cyclohexyl-2-Oxopyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical center, making it a critical building block for modern drug discovery and development. Its pyrrolidinone-carboxylic acid scaffold is highly valued for constructing complex molecules with targeted biological activity. This compound is essential for research and production in the pharmaceutical and fine chemical industries, particularly for synthesizing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, neurological agents, and other active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds and natural product analogs in medicinal chemistry.
• Research & Development: Serves as a crucial reagent in academic and industrial R&D for exploring new chemical entities and biological pathways.
• Peptidomimetics: The pyrrolidinone core is integral in designing peptide mimics for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Potential intermediate in the development of advanced herbicides or fungicides with specific chiral activity.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	4-Cyclohexyl-2-Oxopyrrolidine-3-Carboxylic Acid
CAS No.	1428233-43-5
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	3-Carboxy-4-cyclohexyl-2-pyrrolidinone; 4-Cyclohexyl-3-carboxy-2-pyrrolidinone; 2-Oxo-4-cyclohexylpyrrolidine-3-carboxylic acid; (3S)-4-Cyclohexyl-2-oxopyrrolidine-3-carboxylic acid (for specific enantiomer); 4-Cyclohexyl-2-oxo-3-pyrrolidinecarboxylic acid; Pyrrolidine-3-carboxylic acid, 4-cyclohexyl-2-oxo-; 1428233-43-5
EINECS	Contact for details

Quality Control

Our 4-Cyclohexyl-2-Oxopyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure supply chain integrity and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.