Description

1-[2-(Bromomethyl)Phenoxy]-3,5-Dimethylbenzene is a specialized brominated aromatic ether compound, serving as a crucial advanced pharmaceutical intermediate and organic synthesis building block. Its molecular structure, featuring a reactive bromomethyl group, makes it invaluable for constructing complex molecules through cross-coupling and functionalization reactions. This high-purity intermediate is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where its aromatic backbone contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in homogeneous catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic or structural properties.
• Cross-Coupling Reactions: The bromomethyl group acts as an effective electrophile in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Functional Group Transformation: A versatile starting material for converting the bromomethyl group into other functionalities such as aldehydes, nitriles, or amines.

Basic Information

Product Name	1-[2-(Bromomethyl)Phenoxy]-3,5-Dimethylbenzene
CAS No.	1427460-98-7
Molecular Formula	C₁₅H₁₅BrO
Molecular Weight	291.18 g/mol
Synonyms	2-(Bromomethyl)phenyl 3,5-dimethylphenyl ether; 3,5-Dimethylphenyl 2-(bromomethyl)phenyl ether; 1-Bromomethyl-2-(3,5-dimethylphenoxy)benzene; (2-Bromobenzyl) 3,5-dimethylphenyl ether; o-(Bromomethyl)phenyl 3,5-dimethylphenyl ether; 2-(Bromomethyl)-1-(3,5-dimethylphenoxy)benzene
EINECS	Contact for details

Quality Control

Our production of 1-[2-(Bromomethyl)Phenoxy]-3,5-Dimethylbenzene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical characteristics. Our quality system is designed to meet the exacting standards required for cGMP and non-GMP pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.