Description

6-Chloro-4-Ethynylpyridazin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridazine core functionalized with chloro, ethynyl, and amine groups. This compound matters for its critical role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries need this precise intermediate to drive innovation in drug discovery and material science programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides with specific modes of action.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for the development of specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry and medicinal chemistry studies.

Basic Information

Product Name	6-Chloro-4-Ethynylpyridazin-3-Amine
CAS No.	1425334-86-6
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	6-Chloro-4-ethynyl-3-pyridazinamine; 4-Ethynyl-6-chloropyridazin-3-amine; 3-Amino-6-chloro-4-ethynylpyridazine; 1425334-86-6; 6-Chloro-4-ethynyl-3-aminopyridazine; 4-Ethynyl-6-chloro-3-pyridazinamine; 6-Chloro-4-ethynylpyridazin-3-ylamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Ethynylpyridazin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.