Description

4-Bromo-2-Ethoxy-1-Methanesulfonylbenzene is a high-purity, multi-functional aromatic sulfone building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, ethoxy, and methanesulfonyl substituents, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting sulfone-containing bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromine and sulfone groups enable further functionalization.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring specific electronic or steric properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination to form new carbon-carbon or carbon-heteroatom bonds.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Item	Details
Product Name	4-Bromo-2-Ethoxy-1-Methanesulfonylbenzene
CAS No.	1423037-38-0
Molecular Formula	C9H11BrO3S
Molecular Weight	279.15 g/mol
Synonyms	1-Bromo-4-ethoxy-2-(methylsulfonyl)benzene; 2-Ethoxy-4-bromobenzenesulfonylmethane; 4-Bromo-2-ethoxy-1-(methylsulfonyl)benzene; 4-Bromo-2-ethoxybenzenesulfonylmethane; 4-Bromo-2-ethoxy-α-toluenesulfone; (4-Bromo-2-ethoxyphenyl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Ethoxy-1-Methanesulfonylbenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.