Description

Methyl 6-(Piperazin-1-Yl)Pyridazine-3-Carboxylate Dihydrochloride is a high-purity, pharmaceutically relevant chemical intermediate designed for advanced synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring piperazine and pyridazine motifs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new bioactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthetic routes for potential APIs targeting central nervous system (CNS) disorders, oncology, and other disease areas.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	Methyl 6-(Piperazin-1-Yl)Pyridazine-3-Carboxylate Dihydrochloride
CAS No.	1423025-81-3
Molecular Formula	C10H15Cl2N4O2
Molecular Weight	294.16 g/mol
Synonyms	Methyl 6-(1-Piperazinyl)pyridazine-3-carboxylate dihydrochloride; 6-(Piperazin-1-yl)pyridazine-3-carboxylic acid methyl ester dihydrochloride; Methyl 6-piperazin-1-ylpyridazine-3-carboxylate dihydrochloride; 1423025-81-3; Methyl 6-(piperazin-1-yl)pyridazine-3-carboxylate hydrochloride (1:2); Methyl 6-(1-piperazinyl)-3-pyridazinecarboxylate dihydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 6-(Piperazin-1-Yl)Pyridazine-3-Carboxylate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.