Description

Potassium Trifluoro(4-Methylbenzyl)Borate is a specialized organoboron reagent, specifically a potassium trifluoroborate salt. This compound is valued for its enhanced stability and handling properties compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl motifs in active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic couplings.
• Material Science Research: Serves as a precursor for creating organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Process Chemistry & Scale-up: Its improved stability makes it suitable for optimizing and scaling up manufacturing processes in fine chemical production.
• Academic & Industrial R&D: A fundamental tool in organic synthesis laboratories for method development and exploring new chemical spaces.

Basic Information

Product Name	Potassium Trifluoro(4-Methylbenzyl)Borate
CAS No.	1422539-95-4
Molecular Formula	C8H8BF3K
Molecular Weight	208.06 g/mol
Synonyms	Potassium (4-Methylbenzyl)trifluoroborate; Potassium 4-Methylbenzyltrifluoroborate; (4-Methylbenzyl)trifluoroborate Potassium Salt; Potassium Trifluoro(p-tolylmethyl)borate; Trifluoro(4-methylbenzyl)borate Potassium; K-THFB (4-Methylbenzyl); p-Tolylmethyltrifluoroboronate Potassium
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(4-Methylbenzyl)Borate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity assessment, and KF titration for moisture content, to ensure consistency and high performance in sensitive applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Potassium Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.