Description

Racemic-(4Ar,8S,8Ar)-6-tert-Butyl 8-Ethyl Hexahydro-2H-Pyrano[3,2-C]Pyridine-6,8(7H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex, fused bicyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of potential drug candidates targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Asymmetric Synthesis: Acts as a starting material or intermediate for exploring novel asymmetric transformations and catalysis.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and synthetic methodology.

Basic Information

Product Name	Racemic-(4Ar,8S,8Ar)-6-tert-Butyl 8-Ethyl Hexahydro-2H-Pyrano[3,2-C]Pyridine-6,8(7H)-Dicarboxylate
CAS No.	1422344-50-0
Molecular Formula	C18H29NO5
Molecular Weight	339.43 g/mol
Synonyms	6-tert-Butyl 8-ethyl hexahydro-2H-pyrano[3,2-c]pyridine-6,8(7H)-dicarboxylate; (±)-(4aR,8S,8aR)-6-(tert-Butoxycarbonyl)-8-(ethoxycarbonyl)octahydro-2H-pyrano[3,2-c]pyridine; Hexahydro-2H-pyrano[3,2-c]pyridine-6,8(7H)-dicarboxylic acid, 6-(1,1-dimethylethyl) 8-ethyl ester, (4aR,8S,8aR)-rel-; tert-Butyl 8-ethyl octahydro-2H-pyrano[3,2-c]pyridine-6,8-dicarboxylate; BOC-Protected Pyranopyridine Derivative; CAS 1422344-50-0
EINECS	Contact for details

Quality Control

Our production of Racemic-(4Ar,8S,8Ar)-6-tert-Butyl 8-Ethyl Hexahydro-2H-Pyrano[3,2-C]Pyridine-6,8(7H)-Dicarboxylate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at temperatures between 2°C and 8°C under an inert atmosphere to maintain stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.