Description

4-tert-Butyl 7-Ethyl 6-Oxo-1,4-Oxazepane-4,7-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1422343-95-0. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• API Synthesis: Serves as a crucial building block for constructing the core heterocyclic scaffolds found in various proprietary pharmaceutical compounds.
• Process Development & Scale-Up: Employed in pilot plant and commercial-scale manufacturing processes for new drug candidates under GMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and commercial APIs.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new synthetic methodologies and developing novel pharmacologically active compounds.

Basic Information

Item	Details
Product Name	4-tert-Butyl 7-Ethyl 6-Oxo-1,4-Oxazepane-4,7-Dicarboxylate
CAS No.	1422343-95-0
Molecular Formula	C14H23NO6
Molecular Weight	301.34 g/mol
Synonyms	4-(tert-Butyl) 7-ethyl 6-oxo-1,4-oxazepane-4,7-dicarboxylate; 1,4-Oxazepane-4,7-dicarboxylic acid, 6-oxo-, 4-(1,1-dimethylethyl) 7-ethyl ester; Ethyl 4-(tert-butoxycarbonyl)-6-oxo-1,4-oxazepane-7-carboxylate; 6-Oxo-1,4-oxazepane-4,7-dicarboxylic acid 4-tert-butyl 7-ethyl ester; tert-Butyl ethyl 6-oxo-1,4-oxazepane-4,7-dicarboxylate; BOC-Protected Oxazepane Derivative; Advanced Oxazepane Intermediate
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl 7-Ethyl 6-Oxo-1,4-Oxazepane-4,7-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical development under GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.