Description

(5Ar,9As)-4-(6-Methylpyridazin-3-Yl)Decahydropyrido[4,3-F][1,4]Oxazepine CAS NO 1422063-67-9 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical companies, biotechnology research firms, and contract research organizations (CROs) engaged in the synthesis of new therapeutic agents targeting central nervous system and other complex disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in neuroscience and psychiatric drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Employed in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) requiring its specific fused oxazepine-piperidine structure.
• Biochemical Tool Compound: Serves as a reference standard or a probe molecule in pharmacological assays to study specific receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	(5Ar,9As)-4-(6-Methylpyridazin-3-Yl)Decahydropyrido[4,3-F][1,4]Oxazepine
CAS No.	1422063-67-9
Molecular Formula	C15H22N4O
Molecular Weight	274.36 g/mol
Synonyms	(5Ar,9As)-4-(6-Methylpyridazin-3-yl)decahydro-1H-pyrido[4,3-f][1,4]oxazepine; 4-(6-Methyl-3-pyridazinyl)decahydro-5a,9a-methanopyrido[4,3-f][1,4]oxazepine; Decahydropyrido[4,3-f][1,4]oxazepine, 4-(6-methyl-3-pyridazinyl)-, (5aR,9aS)-rel-; BMS-986165 Impurity; TYK2 Inhibitor Intermediate; Deucravacitinib Related Compound
EINECS	Contact for details

Quality Control

Our (5Ar,9As)-4-(6-Methylpyridazin-3-Yl)Decahydropyrido[4,3-F][1,4]Oxazepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Production can be aligned with ISO and cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.