Description

n-[(8α,9R)-6'-Methoxycinchonan-9-Yl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea is a sophisticated chiral thiourea derivative, synthesized from cinchona alkaloid and glucopyranosyl precursors. This compound is of significant value as a highly selective organocatalyst and a key intermediate in asymmetric synthesis. It is primarily required by research institutions and pharmaceutical companies engaged in the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Asymmetric Organocatalysis: Acts as a bifunctional catalyst for enantioselective reactions, such as Michael additions, Mannich reactions, and aldol condensations.
• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex chiral drug molecules.
• Ligand for Metal Complexes: Can be utilized to create chiral ligands for transition metal catalysis, enhancing stereocontrol.
• Methodology Development: Used in academic and industrial R&D for developing new synthetic methodologies in organic chemistry.
• Chiral Stationary Phase Precursor: Investigated for potential use in the development of materials for chiral chromatography separations.
• Chemical Biology Probe: Employed in studies to understand and modulate biological processes through specific molecular interactions.

Basic Information

Product Name	n-[(8α,9R)-6'-Methoxycinchonan-9-Yl]-N'-(2,3,4,6-Tetra-o-Acetyl-β-D-Glucopyranosyl)-Thiourea
CAS No.	1421852-79-0
Molecular Formula	C34H43N3O10S
Molecular Weight	685.78 g/mol
Synonyms	(8α,9R)-N-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)carbamothioyl]-6'-methoxycinchonan-9-amine; Cinchona Alkaloid Thiourea Derivative; Acetylated Glucosyl Cinchona Thiourea; Chiral Thiourea Organocatalyst; 6'-Methoxycinchonan-9-yl Glucopyranosyl Thiourea; Asymmetric Synthesis Catalyst; 1421852-79-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.