Description

(3R,4S)-4-Amino-3-(Methoxy)Tetrahydropyran CAS NO 1421066-70-7 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. This compound is essential for the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex molecular architectures with high enantiomeric purity in medicinal chemistry.
• Agrochemical Research: Used in the development of advanced, stereospecific pesticides and herbicides.
• Catalyst Ligand Preparation: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Academic & Process R&D: Employed in university and industrial laboratories for method development and scaling novel synthetic routes.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(3R,4S)-4-Amino-3-(Methoxy)Tetrahydropyran
CAS No.	1421066-70-7
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(3R,4S)-4-Amino-3-methoxytetrahydro-2H-pyran; 3-Methoxy-4-aminotetrahydropyran (stereospecific); (3R,4S)-3-Methoxy-4-aminotetrahydropyran; 4-Amino-3-methoxytetrahydropyran; Tetrahydro-2H-pyran-4-amine, 3-methoxy-, (3R,4S)-; 1421066-70-7; (3R-cis)-4-Amino-3-methoxytetrahydropyran
EINECS	Contact for details

Quality Control

Our (3R,4S)-4-Amino-3-(Methoxy)Tetrahydropyran is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.