Description

2,4-Dibromo-6-[( E )-[[(1 R ,2 R )-2-(Isoindolin-2-Yl)-1,2-Diphenylethyl]Imino]Methyl]Phenol is a sophisticated chiral organic compound featuring a brominated phenolic Schiff base structure, designed for advanced chemical synthesis and research. This high-value intermediate is critical for applications requiring precise stereochemical control and functional group manipulation. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Catalyst Ligand Precursor: The chiral diamine and phenolic imine structure makes it a valuable precursor for developing novel ligands in transition metal catalysis for enantioselective reactions.
• Organic Electronic Material Research: Used in exploratory research for organic semiconductors or charge-transport materials due to its conjugated system and bromine substituents.
• Advanced Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular architectures, including natural product analogs.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories serving the pharmaceutical sector.

Basic Information

Product Name	2,4-Dibromo-6-[( E )-[[(1 R ,2 R )-2-(Isoindolin-2-Yl)-1,2-Diphenylethyl]Imino]Methyl]Phenol
CAS No.	1420042-07-4
Molecular Formula	C29H22Br2N2O
Molecular Weight	574.31 g/mol
Synonyms	(1R,2R)-N-((3,5-Dibromo-2-hydroxyphenyl)methylene)-2-(isoindolin-2-yl)-1,2-diphenylethanamine; (R,R)-2,4-Dibromo-6-(((2-(isoindolin-2-yl)-1,2-diphenylethyl)imino)methyl)phenol; Phenol, 2,4-dibromo-6-[(E)-[[(1R,2R)-2-(1,3-dihydro-2H-isoindol-2-yl)-1,2-diphenylethyl]imino]methyl]-; Chiral Brominated Phenolic Schiff Base; (R,R)-DPEN-Derived Bromo-Schiff Base
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-[( E )-[[(1 R ,2 R )-2-(Isoindolin-2-Yl)-1,2-Diphenylethyl]Imino]Methyl]Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.