Description

n-Methyl-n-[4-(Trimethylsilyl)Phenyl]Pivalamide is a specialized organosilicon compound featuring a unique pivalamide-protected aniline structure. This chemical serves as a valuable high-purity synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring silicon-containing or sterically hindered aromatic amine motifs.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides where the trimethylsilyl group can modulate biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, silicones, and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis, where the silyl and amide groups can influence metal coordination and catalytic performance.
• Chemical Research (R&D): A versatile reagent for academic and industrial research exploring new synthetic methodologies, including cross-coupling reactions and C-H functionalization.
• Protecting Group Strategy: The pivalamide group can act as a protecting group for amines in multi-step synthetic sequences, with the silyl moiety offering additional handles for further modification.

Basic Information

Product Name	n-Methyl-n-[4-(Trimethylsilyl)Phenyl]Pivalamide
CAS No.	1418117-84-6
Molecular Formula	C15H25NOSi
Molecular Weight	263.45 g/mol
Synonyms	N-Methyl-N-[4-(trimethylsilyl)phenyl]-2,2-dimethylpropanamide; N-Methyl-N-(4-(trimethylsilyl)phenyl)pivalamide; Pivalic Acid N-Methyl-N-[4-(Trimethylsilyl)Phenyl]Amide; 2,2-Dimethyl-N-methyl-N-[4-(trimethylsilyl)phenyl]propanamide; 4-(Trimethylsilyl)-N-methyl-N-pivaloylaniline; TMS-Protected N-Methyl Pivalanilide
EINECS	Contact for details

Quality Control

Our n-Methyl-n-[4-(Trimethylsilyl)Phenyl]Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.