Description

[1-(Pyridine-2-Sulfonyl)-Pyrrolidin-2-Yl]-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide-linked pyrrolidine-pyridine hybrid structure. This compound matters for its critical role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D and fine chemical manufacturers need it to develop next-generation drug candidates targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Protease Inhibitor Research: Used in the development of inhibitors targeting specific enzymes, such as kinases or proteases, due to its sulfonamide and heterocyclic motifs.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in pharmaceutical R&D.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical component for fine chemical suppliers offering bespoke synthesis services for the pharmaceutical industry.
• Academic & Industrial Research: Employed in research institutions and corporate R&D labs for exploratory chemistry and new methodology development.

Basic Information

Product Name	[1-(Pyridine-2-Sulfonyl)-Pyrrolidin-2-Yl]-Methanol
CAS No.	1417793-68-0
Molecular Formula	C10H14N2O3S
Molecular Weight	242.30 g/mol
Synonyms	1-(Pyridin-2-ylsulfonyl)pyrrolidin-2-ylmethanol; 2-Pyrrolidinemethanol, 1-(2-pyridinylsulfonyl)-; (1-(Pyridine-2-sulfonyl)pyrrolidin-2-yl)methanol; 1-(Pyridine-2-sulfonyl)-2-pyrrolidinemethanol; 1-(2-Pyridylsulfonyl)-2-pyrrolidinemethanol; 1-(2-Pyridinylsulfonyl)-2-pyrrolidinemethanol; 1-(Pyridin-2-sulfonyl)pyrrolidin-2-ylmethanol
EINECS	Contact for details

Quality Control

Our [1-(Pyridine-2-Sulfonyl)-Pyrrolidin-2-Yl]-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.