Description

5-(Tributylstannyl)-1,2-thiazole is a specialized organotin reagent featuring a stannyl group attached to a thiazole heterocycle. This compound is a critical building block in modern synthetic organic chemistry, particularly for Stille cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing the thiazole moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Stille Cross-Coupling Reactions: Serves as a versatile organotin coupling partner for the palladium-catalyzed formation of C-C bonds with organic halides or triflates.
• Ligand and Catalyst Development: Utilized as a starting material for synthesizing novel ligands and organometallic catalysts.
• Chemical Research: A valuable tool for academic and industrial R&D in synthetic methodology development and complex molecule construction.

Basic Information

Product Name	5-(Tributylstannyl)-1,2-thiazole
CAS No.	1416853-22-9
Molecular Formula	C15H29NSSn
Molecular Weight	374.15 g/mol
Synonyms	1,2-Thiazole, 5-(tributylstannyl)-; 5-Tributylstannyl-1,2-thiazole; Tributyl(1,2-thiazol-5-yl)stannane; 5-(Tributylstannyl)isothiazole; Stannane, tributyl(1,2-thiazol-5-yl)-; 5-(Tributyltin)-1,2-thiazole; 5-(SnBu3)-1,2-thiazole
EINECS	Contact for details

Quality Control

Our 5-(Tributylstannyl)-1,2-thiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including NMR (1H, 13C, 119Sn), HPLC, and GC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C. Due to its moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.