Description

5-Trimethylstannylisoquinoline is a specialized organotin compound featuring an isoquinoline heterocycle. This organometallic reagent is valued for its role as a key building block in advanced organic synthesis and materials science research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics sectors for cross-coupling reactions and the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in palladium-catalyzed Stille cross-coupling reactions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents.
• Materials Science: Employed in the synthesis of organic semiconductors, conductive polymers, and advanced functional materials.
• Catalyst Ligand Synthesis: Acts as a starting material for creating novel organotin-based ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	5-Trimethylstannylisoquinoline
CAS No.	1416437-23-4
Molecular Formula	C₁₃H₁₇NSn
Molecular Weight	298.0 g/mol (approx.)
Synonyms	Isoquinoline, 5-(trimethylstannyl)-; 5-(Trimethylstannyl)isoquinoline; Trimethyl(isoquinolin-5-yl)stannane; Stannane, trimethyl(5-isoquinolinyl)-; 5-Trimethyltin-isoquinoline; 5-(Trimethyltin)isoquinoline; 5-Isoquinolinyltrimethyltin; (5-Isoquinolinyl)trimethylstannane
EINECS	Contact for details

Quality Control

Our 5-Trimethylstannylisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by NMR (1H, 13C, 119Sn), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen). Due to its hygroscopic and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent condensation and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin Content	39.0 - 40.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.