Description

2-(5-Bromo-2,4-Difluoro-3-Methylphenyl)-5,5-Dimethyl-1,3-Dioxane CAS NO 1416372-35-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and protected diol structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of new therapeutic agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its role in constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in fluorinated compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated phenyl ring.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in catalyst systems.
• Organic Synthesis: Valuable reagent for constructing complex molecules in academic and industrial R&D laboratories.
• Fluorine Chemistry: Essential for introducing difluoro and bromo substituents in strategic positions on aromatic systems.

Basic Information

Product Name	2-(5-Bromo-2,4-Difluoro-3-Methylphenyl)-5,5-Dimethyl-1,3-Dioxane
CAS No.	1416372-35-4
Molecular Formula	C₁₃H₁₅BrF₂O₂
Molecular Weight	321.16 g/mol
Synonyms	5,5-Dimethyl-2-(5-bromo-2,4-difluoro-3-methylphenyl)-1,3-dioxane; 2-(5-Bromo-2,4-difluoro-3-methylphenyl)-5,5-dimethyl-1,3-dioxane; 1,3-Dioxane, 2-(5-bromo-2,4-difluoro-3-methylphenyl)-5,5-dimethyl-; 1416372-35-4; 5-Bromo-2,4-difluoro-3-methylbenzaldehyde ethylene acetal; (5-Bromo-2,4-difluoro-3-methylphenyl)acetaldehyde dimethyl acetal (related structure).
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2,4-Difluoro-3-Methylphenyl)-5,5-Dimethyl-1,3-Dioxane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.